Amelixir™ isn’t just whitening—it’s clinical-grade skin renewal from the inside out.
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Each lyophilized vial of NeuroSynthione™ is powered by eight clinically validated bioactive compounds
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Includes :
One box of Amelixir (8 mL per vial, 12 vials)
One box of NeuroSynthione (5 mL per vial, 12 vials)
At L’ Pavéa en Paris, we believe modern skincare should work in synergy with human biology—deep, precise, and clinically intelligent.
That’s why our research team in Paris has developed a dual-action, clinical-grade dermaceutical system that tackles aging from both neural-metabolic and cellular-regenerative angles. Designed to be used together for optimal performance, our flagship products — NeuroSynthione® and Amelixir® — represent a next-generation approach to bioactive skin renewal, systemic whitening, and neuro-cosmetic balance.
Used in tandem, these two formulas deliver a compounded effect:
– NeuroSynthione® acts as a neural-antioxidant shield, preventing premature aging at the mitochondrial and redox level.
– Amelixir® works at the cellular rejuvenation layer, targeting pigmentation, microcirculation, and immune resilience.
HyperAnthocyanin® provides 30 times the antioxidant potency of natural anthocyanins, neutralizing free radicals while enhancing microcirculation and oxygen delivery to skin cells. This dual action corrects uneven tone and strengthens capillary networks, visibly brightening the skin and creating a “glass-skin” effect. In a study published in the Journal of Functional Foods (2023), anthocyanin supplementation was shown to significantly improve skin perfusion and radiance, particularly in individuals with oxidative stress-related dullness.
NAD⁺, often referred to as the “molecule of youth,” is fundamental for DNA repair, mitochondrial energy production, and pigmentation regulation. By activating SIRT1 pathways, it reduces melanin formation while rejuvenating cellular energy systems. Research in Nature Communications (2022) demonstrated that NAD⁺ supplementation restored mitochondrial function, reversed cellular aging markers, and reduced oxidative pigmentation triggers, confirming its powerful role in revitalizing skin from within.
L-Methionine is a critical precursor to glutathione, the body’s master whitening and detoxifying antioxidant. By boosting glutathione synthesis, it neutralizes free radicals and addresses pigmentation at its oxidative source. Findings from the Journal of Clinical Biochemistry (2021) highlight its ability to enhance glutathione activity, significantly improving skin clarity and reducing discoloration caused by oxidative stress.
This high-dose, sustained-release form of Vitamin C inhibits tyrosinase to block melanin synthesis while stimulating collagen production for firmer, brighter skin. A clinical trial published in Dermatologic Therapy (2023) confirmed that pharmaceutical-grade Vitamin C reduced pigmentation irregularities and improved collagen density within 8 weeks, reinforcing its dual action in both brightening and anti-aging.
Malic acid accelerates epidermal turnover, effectively shedding pigmented keratinocytes and revealing fresher, more even-toned skin. It also supports cellular energy metabolism to improve detoxification and skin renewal. The International Journal of Dermatology (2021) reported that malic acid enhanced skin regeneration and visibly diminished hyperpigmentation spots with consistent use.
L-Glutamic acid plays a key role in regulating intracellular pH and detoxifying skin cells, helping reduce oxidative dullness and improve radiance. According to Dermato-Endocrinology (2022), glutamic acid supplementation enhanced oxidative balance and visibly boosted overall skin brightness, making it essential for a luminous complexion.
The world’s first AI-engineered antioxidant molecule, designed using the AURORA molecular synthesis platform.
How it works: Targets mitochondrial oxidative stress with ultra-rapid ROS scavenging and deep dermal penetration.
Proof: Demonstrated 92% reduction in intracellular ROS within 6 hours—32× faster than Vitamin C and 26× faster than glutathione (in vitro).
Clinical Impact: Protects mitochondrial DNA, boosts ATP energy production, and prevents neurogenic aging triggers such as oxidative pigmentation and barrier disruption.
(L’ Pavéa Research Alliance, Paris–Osaka 2024)
Function: Vital mineral cofactor supporting over 300 enzymatic reactions, including collagen synthesis and barrier repair.
Proof: Shown to improve hydration and reduce transepidermal water loss by enhancing lipid bilayer stability in keratinocytes. (ResearchGate, Interaction of Mineral Salts with Skin, 2023)
Function: Potent polyphenol from olive leaf extract with antioxidant, anti-inflammatory, and anti-aging effects.
Proof: In keratinocyte studies, oleuropein reduced IL‑6 by 45% and decreased ROS load by 9%, promoting skin repair and wound healing. (PubMed: Oleuropein & Pyroptosis Inhibition, 2024)
Function: High-potency flavonoid that neutralizes ROS, calms inflammation, and supports pigmentation balance.
Proof: A 2024 meta-analysis of 65 studies confirmed quercetin’s ability to enhance SOD/catalase activity, inhibit tyrosinase (pigment control), and boost collagen regeneration.
(PubMed: Quercetin & Skin Health, 2024)
Function: Boosts NAD⁺ pathways essential for DNA repair, skin barrier reinforcement, and improved texture.
Proof: Clinical dermatology trials show niacinamide reduces hyperpigmentation, strengthens skin resilience, and enhances elasticity in 8–12 weeks.(Journal of Cosmetic Dermatology, 2022)
Function: Key coenzyme in mitochondrial redox reactions, supporting detoxification and energy metabolism.
Proof: Riboflavin supplementation improves oxidative enzyme activity, reducing cellular stress in dermal fibroblasts. (Nutrients Journal, 2023)
Function: Primary defense enzyme against superoxide radicals, restoring oxidative balance in aging cells.
Proof: Animal models show SOD overexpression thickens dermis and boosts collagen by activating AMPK and Nrf2 pathways, slowing visible skin aging.
(PMC: SOD & Dermal Aging Prevention, 2023)
Function: Black tea bioflavonoids proven to improve microvascular circulation and oxygen delivery to skin.
Proof: Studies link theaflavins to improved collagen density and reduction in photoaging biomarkers due to their antioxidant synergy. (MDPI: Theaflavins & Skin Oxygenation, 2023)
First AI-Engineered Antioxidant Molecule (NeuroSynthione®):
Systemic Whitening & Cellular Renewal (Amelixir®):
Medical-Grade Formulations Trusted by Professionals:
Synergistic Dual-Therapy Advantage:
Amelixir®
isn’t just whitening—it’s clinical-grade skin renewal from the inside out. Formulated with AI-enhanced bioactives and pharmaceutical-grade nutrients, it delivers head-to-toe radiance, mitochondrial repair, and long-term skin health.
NeuroSynthione® Advanced Neuro-Antioxidant Complex
Each lyophilized vial of NeuroSynthione® is powered by eight clinically validated bioactive compounds, formulated to neutralize oxidative stress, rejuvenate cellular energy, and protect skin at its mitochondrial and neural roots.
Mitochondrial Revitalization
Delivers full-body brightening for uniform radiance from face to body
Address:
L’ Pavéa en Paris
06 Bd Haussmann,
75009 Paris, France
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