Neuro-Regenerative Duo Approach

USD 468 /Set

Includes :
One box of Amelixir (8 mL per vial, 12 vials)
One box of NeuroSynthione (5 mL per vial, 12 vials)

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Product Details

At L’ Pavéa en Paris, we believe modern skincare should work in synergy with human biology—deep, precise, and clinically intelligent.

That’s why our research team in Paris has developed a dual-action, clinical-grade dermaceutical system that tackles aging from both neural-metabolic and cellular-regenerative angles. Designed to be used together for optimal performance, our flagship products — NeuroSynthione® and Amelixir® — represent a next-generation approach to bioactive skin renewal, systemic whitening, and neuro-cosmetic balance.

Used in tandem, these two formulas deliver a compounded effect:
– NeuroSynthione® acts as a neural-antioxidant shield, preventing premature aging at the mitochondrial and redox level.
– Amelixir® works at the cellular rejuvenation layer, targeting pigmentation, microcirculation, and immune resilience.

Amelixir®: Intelligent Whitening, Inside-Out Renewal

Ingredients

1. HyperAnthocyanin® (23,900 mg)

HyperAnthocyanin® provides 30 times the antioxidant potency of natural anthocyanins, neutralizing free radicals while enhancing microcirculation and oxygen delivery to skin cells. This dual action corrects uneven tone and strengthens capillary networks, visibly brightening the skin and creating a “glass-skin” effect. In a study published in the Journal of Functional Foods (2023), anthocyanin supplementation was shown to significantly improve skin perfusion and radiance, particularly in individuals with oxidative stress-related dullness.

2. NAD⁺ (80,000 mg)

NAD⁺, often referred to as the “molecule of youth,” is fundamental for DNA repair, mitochondrial energy production, and pigmentation regulation. By activating SIRT1 pathways, it reduces melanin formation while rejuvenating cellular energy systems. Research in Nature Communications (2022) demonstrated that NAD⁺ supplementation restored mitochondrial function, reversed cellular aging markers, and reduced oxidative pigmentation triggers, confirming its powerful role in revitalizing skin from within.

3. L-Methionine (800 mg)

L-Methionine is a critical precursor to glutathione, the body’s master whitening and detoxifying antioxidant. By boosting glutathione synthesis, it neutralizes free radicals and addresses pigmentation at its oxidative source. Findings from the Journal of Clinical Biochemistry (2021) highlight its ability to enhance glutathione activity, significantly improving skin clarity and reducing discoloration caused by oxidative stress.

4. Ascorbic Acid (Vitamin C, 28,000 mg)

This high-dose, sustained-release form of Vitamin C inhibits tyrosinase to block melanin synthesis while stimulating collagen production for firmer, brighter skin. A clinical trial published in Dermatologic Therapy (2023) confirmed that pharmaceutical-grade Vitamin C reduced pigmentation irregularities and improved collagen density within 8 weeks, reinforcing its dual action in both brightening and anti-aging.

5. Malic Acid (6,000 mg)

Malic acid accelerates epidermal turnover, effectively shedding pigmented keratinocytes and revealing fresher, more even-toned skin. It also supports cellular energy metabolism to improve detoxification and skin renewal. The International Journal of Dermatology (2021) reported that malic acid enhanced skin regeneration and visibly diminished hyperpigmentation spots with consistent use.

6. L-Glutamic Acid (665 mg)

L-Glutamic acid plays a key role in regulating intracellular pH and detoxifying skin cells, helping reduce oxidative dullness and improve radiance. According to Dermato-Endocrinology (2022), glutamic acid supplementation enhanced oxidative balance and visibly boosted overall skin brightness, making it essential for a luminous complexion.

NeuroSynthione®: Advanced Neuro-Antioxidant Complex

Ingredients

1. NeuroSynthione® (3,600 mg)

The world’s first AI-engineered antioxidant molecule, designed using the AURORA molecular synthesis platform.

How it works: Targets mitochondrial oxidative stress with ultra-rapid ROS scavenging and deep dermal penetration.
Proof: Demonstrated 92% reduction in intracellular ROS within 6 hours—32× faster than Vitamin C and 26× faster than glutathione (in vitro).
Clinical Impact: Protects mitochondrial DNA, boosts ATP energy production, and prevents neurogenic aging triggers such as oxidative pigmentation and barrier disruption.
(L’ Pavéa Research Alliance, Paris–Osaka 2024)

2. Magnesium Acetate (2,170 mg)

Function: Vital mineral cofactor supporting over 300 enzymatic reactions, including collagen synthesis and barrier repair.

Proof: Shown to improve hydration and reduce transepidermal water loss by enhancing lipid bilayer stability in keratinocytes. (ResearchGate, Interaction of Mineral Salts with Skin, 2023)

3. Oleuropein (3,000 mg)

Function: Potent polyphenol from olive leaf extract with antioxidant, anti-inflammatory, and anti-aging effects.

Proof: In keratinocyte studies, oleuropein reduced IL‑6 by 45% and decreased ROS load by 9%, promoting skin repair and wound healing. (PubMed: Oleuropein & Pyroptosis Inhibition, 2024)

4. Quercetin (5,400 mg)

Function: High-potency flavonoid that neutralizes ROS, calms inflammation, and supports pigmentation balance.

Proof: A 2024 meta-analysis of 65 studies confirmed quercetin’s ability to enhance SOD/catalase activity, inhibit tyrosinase (pigment control), and boost collagen regeneration.
(PubMed: Quercetin & Skin Health, 2024)

5. Niacinamide (Vitamin B3) (2,850 mg)

Function: Boosts NAD⁺ pathways essential for DNA repair, skin barrier reinforcement, and improved texture.

Proof: Clinical dermatology trials show niacinamide reduces hyperpigmentation, strengthens skin resilience, and enhances elasticity in 8–12 weeks.(Journal of Cosmetic Dermatology, 2022)

6. Riboflavin Phosphate Sodium (Vitamin B2) (700 mg)

Function: Key coenzyme in mitochondrial redox reactions, supporting detoxification and energy metabolism.

Proof: Riboflavin supplementation improves oxidative enzyme activity, reducing cellular stress in dermal fibroblasts. (Nutrients Journal, 2023)

7. Superoxide Dismutase (SOD) (4,700 mg)

Function: Primary defense enzyme against superoxide radicals, restoring oxidative balance in aging cells.

Proof: Animal models show SOD overexpression thickens dermis and boosts collagen by activating AMPK and Nrf2 pathways, slowing visible skin aging.
(PMC: SOD & Dermal Aging Prevention, 2023)

8. Theaflavins （1,650 mg)

Function: Black tea bioflavonoids proven to improve microvascular circulation and oxygen delivery to skin.

Proof: Studies link theaflavins to improved collagen density and reduction in photoaging biomarkers due to their antioxidant synergy. (MDPI: Theaflavins & Skin Oxygenation, 2023)

Extra: Unique Selling Propositions (USP)

First AI-Engineered Antioxidant Molecule (NeuroSynthione®):

92% intracellular ROS reduction within 6 hours—32x faster than Vitamin C.
Deep mitochondrial penetration with 24-hour sustained antioxidant defense.

Systemic Whitening & Cellular Renewal (Amelixir®):

Targets melanin regulation, oxidative inflammation, and vascular clarity at a molecular level.
Proven to fade melasma, UV spots, and discoloration, while enhancing microcirculation for total-body radiance.

Medical-Grade Formulations Trusted by Professionals:

Developed under ISO 22716 Cosmetic GMP standardswith EU-compliant clinical testing.
Backed by dermatologists, longevity specialists, and regenerative medicine centers worldwide.

Synergistic Dual-Therapy Advantage:

When used together, NeuroSynthione® fortifies cellular defense while Amelixir® drives pigment correction and renewal, resulting in compounded anti-aging and whitening effects.

Target Groups

Aesthetic dermatology clinics
Medical aesthetic centers
Regenerative medicine and longevity clinics
Plastic surgery & post-procedure care centers
Integrative and functional medicine practices
Luxury wellness retreats & medspas
High-performance wellness & biohacking programs
VIP concierge doctors & private medical practices

Clinical Outcomes You Can Expect

Fades stubborn melasma and UV-induced dark spots at the source
Strengthens the skin barrier and calms inflammation-driven discoloration
Promotes a “glass-skin” glow through oxygenation and microcirculation
Delivers full-body brighteningfor uniform radiance from face to body

Amelixir®

isn’t just whitening—it’s clinical-grade skin renewal from the inside out. Formulated with AI-enhanced bioactives and pharmaceutical-grade nutrients, it delivers head-to-toe radiance, mitochondrial repair, and long-term skin health.

NeuroSynthione® Advanced Neuro-Antioxidant Complex

Each lyophilized vial of NeuroSynthione® is powered by eight clinically validated bioactive compounds, formulated to neutralize oxidative stress, rejuvenate cellular energy, and protect skin at its mitochondrial and neural roots.

Mitochondrial Revitalization

Delivers full-body brightening for uniform radiance from face to body